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Phase 2 trial data published in 2023 in the New England Journal of Medicine (Jastreboff et al., NEJM 2023) reported mean weight reductions of up to approximately 24% over 48 weeks in adults with obesity notably higher than results seen with currently approved agents
Its often praised for being gentle on the stomach, and others like that it works even without strict skincare regimens
Light exposure: Store in original packaging away from direct light
New nausea, vomiting, headache, vision changes, abdominal pain, swelling, high blood pressure, bleeding, leaking fluid, or reduced fetal movement can indicate an obstetric emergency and should not be treated as routine dehydration
By 8 mg, the weight-loss curve has reached about 94% of the 12 mg result because the downstream response approaches its ceiling before receptor occupancy does. None of those occupancy numbers are fixed, though
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